| Term: | retina RIG-I signaling pathway |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | retina |
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| Synonyms: | retinas |
| Definition: | Multi-tissue structure that contains the retinal neural layer and the retinal pigmented epithelium, and develops from the optic cup. |
| Ontology: | Anatomy Ontology [ZFA:0000152] |
| Name: | RIG-I signaling pathway |
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| Synonyms: | DDX58 signaling pathway, retinoic acid inducible gene I signaling pathway, RIG-I signalling pathway, RIG-I-like receptor (RLR) signaling pathway, RIG-like helicase signaling pathway, RIG-like receptor signaling pathway, RLH signaling pathway, RLR signaling pathway |
| Definition: | The series of molecular signals initiated by the binding ssRNA or dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58). RIG-I detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. |
| Ontology: | GO: Biological Process [GO:0039529] QuickGO AmiGO |