RIG-I signaling pathway

Term ID

GO:0039529

Synonyms

• DDX58 signaling pathway
• retinoic acid inducible gene I signaling pathway
• RIG-I signalling pathway
• RIG-I-like receptor (RLR) signaling pathway
• RIG-like helicase signaling pathway
• RIG-like receptor signaling pathway
• RLH signaling pathway
• RLR signaling pathway

Definition

The series of molecular signals initiated by the binding ssRNA or dsRNA from another organism to the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58). RIG-I detects RNA synthesized during viral replication or shed by non-viral pathogens, and triggers a signaling pathway to protect the host against infection, for example by inducing the expression of cytokines. (4)

References

Ontology

GO: Biological Process    QuickGO    AmiGO