| Term: | brain MAPK cascade |
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| Note: | This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name. |
| Name: | brain |
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| Synonyms: | brain structure |
| Definition: | Cavitated compound organ which is comprised of gray and white matter and surrounds the cerebral ventricular system. |
| Ontology: | Anatomy Ontology [ZFA:0000008] |
| Name: | MAPK cascade |
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| Synonyms: | ERK/MAPK cascade, MAP kinase cascade, MAP kinase kinase kinase cascade, MAPK signal transduction, MAPK signaling, MAPK signalling, MAPKKK cascade, MAPKKK cascade during sporulation, mitogen-activated protein kinase cascade |
| Definition: | An intracellular protein kinase cascade containing at least a MAP kinase (MAPK). It starts with the activation of a MAP3K, and the consecutive activation of a MPK2K and a MAPK. The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinase in the downstream tier to transmit a signal within a cell. |
| Ontology: | GO: Biological Process [GO:0000165] QuickGO AmiGO |