Gene
fsta
- ID
- ZDB-GENE-990714-11
- Name
- follistatin a
- Symbol
- fsta Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have activin binding activity. Involved in determination of dorsal identity; embryonic organ morphogenesis; and midbrain development. Predicted to localize to extracellular space. Human ortholog(s) of this gene implicated in polycystic ovary syndrome. Is expressed in several structures, including central nervous system; head; mesoderm; neural tube; and ovary. Orthologous to human FST (follistatin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 51 figures from 35 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb446 (47 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR002350 | Kazal domain |
| Domain | IPR003645 | Follistatin-like, N-terminal |
| Domain | IPR015369 | Follistatin/Osteonectin EGF domain |
| Domain | IPR017878 | TB domain |
| Family | IPR050653 | Protease Inhibitors and Growth Factor Antagonists |
| Homologous_superfamily | IPR036058 | Kazal domain superfamily |
| Homologous_superfamily | IPR036773 | TGF-beta binding (TB) domain superfamily |
Domain Details Per Protein
| Protein | Length | Follistatin-like, N-terminal | Follistatin/Osteonectin EGF domain | Kazal domain | Kazal domain superfamily | Protease Inhibitors and Growth Factor Antagonists | TB domain | TGF-beta binding (TB) domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AZS1
|
327 | |||||||
|
UniProtKB:Q9YHV4
|
322 | |||||||
|
UniProtKB:A0A8M2BCI8
|
349 |
Interactions and Pathways
No data available
Plasmids
No data available