Gene
hs6st1a
- ID
- ZDB-GENE-050524-1
- Name
- heparan sulfate 6-O-sulfotransferase 1a
- Symbol
- hs6st1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Exhibits heparan sulfate 6-O-sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 15 with or without anosmia. Is expressed in several structures, including immature eye; nervous system; neural keel; neural tube; and polster. Orthologous to human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110038 (11 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hypogonadotropic hypogonadism 15 with or without anosmia | Alliance | {Hypogonadotropic hypogonadism 15 with or without anosmia} | 614880 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Heparan sulphate 6-sulfotransferase/Protein-tyrosine sulfotransferase | P-loop containing nucleoside triphosphate hydrolase | Sulfotransferase |
|---|---|---|---|---|
|
UniProtKB:Q56UJ5
|
413 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
hs6st1a-201
(1)
|
Ensembl | 737 nt | ||
| mRNA |
hs6st1a-202
(1)
|
Ensembl | 1,242 nt |
Interactions and Pathways
No data available
Plasmids
No data available