ZFIN is now using GRCz12tu for Genomic Data

Gene

mical3a

ID

ZDB-GENE-050126-2

Name

microtubule associated monooxygenase, calponin and LIM domain containing 3a

Symbol

mical3a Nomenclature History

Previous Names

mical3

Type

protein_coding_gene

Location

Chr: 18 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable FAD binding activity; actin binding activity; and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Predicted to be involved in actin filament depolymerization. Predicted to be located in nucleus. Is expressed in several structures, including cardiovascular system; pectoral fin; pectoral fin bud; proctodeum; and retina. Orthologous to human MICAL3 (microtubule associated monooxygenase, calponin and LIM domain containing 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Xue et al., 2010

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mical3a Human Ortholog

No data available

Associated With mical3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001715	Calponin homology domain
Domain	IPR001781	Zinc finger, LIM-type
Domain	IPR002938	FAD-binding domain
Domain	IPR022735	bMERB domain
Domain	IPR057494	[F-actin]-monooxygenase MICAL1-3-like, Rossman domain
Family	IPR050540	F-actin Monooxygenase Mical
Homologous_superfamily	IPR036188	FAD/NAD(P)-binding domain superfamily
Homologous_superfamily	IPR036872	CH domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PVP9	InterPro	2124
UniProtKB:A0A8M9PCY4	InterPro	2522
UniProtKB:A0A8M9PME7	InterPro	2154
UniProtKB:F1QH17	InterPro	1994
UniProtKB:A0AB32T8R9	InterPro	2113
UniProtKB:A0AB32T8Y4	InterPro	2170
UniProtKB:A0AB32TCE2	InterPro	2114
UniProtKB:A0AC58HVB3	InterPro	2288
UniProtKB:A0AC58HVB6	InterPro	2268
UniProtKB:A0AC58HVB7	InterPro	2287
UniProtKB:A0AC58HVC1	InterPro	2266
UniProtKB:A0AC58HVC2	InterPro	2260
UniProtKB:A0AC58HVC4	InterPro	2267
UniProtKB:A0AC58HVC6	InterPro	2522
UniProtKB:A0AC58HVC7	InterPro	2287
UniProtKB:A0AC58HVC8	InterPro	2297
UniProtKB:A0AC58HVD0	InterPro	2288
UniProtKB:A0AC58HVD2	InterPro	2296
UniProtKB:A0AC58HVD4	InterPro	2269
UniProtKB:A0AC58HVD5	InterPro	2213
UniProtKB:A0AC58HVD6	InterPro	2113
UniProtKB:A0AC58HVD7	InterPro	2205
UniProtKB:A0AC58HVD8	InterPro	2048
UniProtKB:A0AC58HVE1	InterPro	2212
UniProtKB:A0AC58HVE2	InterPro	2212
UniProtKB:A0AC58HVE3	InterPro	2078
UniProtKB:A0AC58HVE4	InterPro	2228
UniProtKB:A0AC58HVE5	InterPro	2259
UniProtKB:A0AC58HVE6	InterPro	2238
UniProtKB:A0AC58HVE7	InterPro	2229
UniProtKB:A0AC58HVE8	InterPro	2205
UniProtKB:A0AC58HVE9	InterPro	2140
UniProtKB:A0AC58HVF0	InterPro	2260
UniProtKB:A0AC58HVF1	InterPro	2048
UniProtKB:A0AC58HVF2	InterPro	2011
UniProtKB:A0AC58HVF4	InterPro	2030
UniProtKB:A0AC58HVF5	InterPro	1976
UniProtKB:A0AC58HVF6	InterPro	2047
UniProtKB:A0AC58HVF7	InterPro	1998
UniProtKB:A0AC58HVF9	InterPro	2048
UniProtKB:A0AC58HVG1	InterPro	2057
UniProtKB:A0AC58HVG2	InterPro	2048
UniProtKB:A0AC58HVG3	InterPro	2047
UniProtKB:A0AC58HVG5	InterPro	2075
UniProtKB:A0AC58HVG6	InterPro	2032
UniProtKB:A0AC58HVG7	InterPro	1959
UniProtKB:A0AC58HVG8	InterPro	2015
UniProtKB:A0AC58HVH0	InterPro	1960
UniProtKB:A0AC58HVH2	InterPro	2286
UniProtKB:A0AC58HVH4	InterPro	1977
UniProtKB:A0AC58HVH6	InterPro	1959
UniProtKB:A0AC58HVH7	InterPro	1994
UniProtKB:A0AC58HVI1	InterPro	1976
UniProtKB:A0AC58HVJ0	InterPro	2206
UniProtKB:A0AC58HVK6	InterPro	2040

Transcripts

Genome Browsers

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mical3a-203 (1) Ensembl	Ensembl	589 nt	Select Tool ZFIN BLAST
mRNA	mical3a-204 (1) Ensembl	Ensembl	3,541 nt	Select Tool ZFIN BLAST
mRNA	mical3a-205 (1) Ensembl	Ensembl	5,985 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance

Citations