Gene

flad1

ID

ZDB-GENE-040822-44

Name

flavin adenine dinucleotide synthetase 1

Symbol

flad1 Nomenclature History

Previous Names

fa92c06
wu:fa92c06
zgc:91843

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have FMN adenylyltransferase activity. Predicted to be involved in FAD biosynthetic process. Predicted to localize to cytoplasm. Orthologous to human FLAD1 (flavin adenine dinucleotide synthetase 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:91843 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With flad1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Lipid storage myopathy due to flavin adenine dinucleotide synthetase deficiency	255100

Associated With flad1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001453	MoaB/Mog domain
Domain	IPR002500	Phosphoadenosine phosphosulphate reductase
Domain	IPR006612	THAP-type zinc finger
Family	IPR012183	FAD synthetase with the MoaB/Mog domain
Homologous_superfamily	IPR014729	Rossmann-like alpha/beta/alpha sandwich fold
Homologous_superfamily	IPR036425	MoaB/Mog-like domain superfamily
Homologous_superfamily	IPR038441	THAP-type zinc finger superfamily

Domain Details Per Protein

Protein	Length	FAD synthetase with the MoaB/Mog domain	MoaB/Mog domain	MoaB/Mog-like domain superfamily	Phosphoadenosine phosphosulphate reductase	Rossmann-like alpha/beta/alpha sandwich fold	THAP-type zinc finger	THAP-type zinc finger superfamily
UniProtKB:A0A8M2BH00 InterPro	521
UniProtKB:Q68EH8 InterPro	497
UniProtKB:A0A0R4INK4 InterPro	614

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	flad1-201 (1) Ensembl	Ensembl	2,094 nt	Select Tool
mRNA	flad1-202 (1) Ensembl	Ensembl	1,120 nt	Select Tool
mRNA	flad1-204 (1) Ensembl	Ensembl	824 nt	Select Tool
mRNA	flad1-205 (1) Ensembl	Ensembl	4,653 nt	Select Tool ZFIN BLAST
ncRNA	flad1-004 (1) Ensembl	Ensembl	768 nt	Select Tool

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations