Gene

pef1

ID

ZDB-GENE-040801-259

Name

penta-EF-hand domain containing 1

Symbol

pef1 Nomenclature History

Previous Names

zgc:100787 (1)

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have protein binding activity, bridging involved in substrate recognition for ubiquitination. Predicted to be involved in COPII vesicle coating; mesenchymal cell differentiation; and positive regulation of protein monoubiquitination. Predicted to localize to COPII vesicle coat and Cul3-RING ubiquitin ligase complex. Orthologous to human PEF1 (penta-EF-hand domain containing 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6893932 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pef1 Human Ortholog

No data available

Associated With pef1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018247	EF-Hand 1, calcium-binding site
Domain	IPR002048	EF-hand domain
Family	IPR051426	Peflin/Sorcin Calcium-Binding
Homologous_superfamily	IPR011992	EF-hand domain pair