Gene
fbxw11b
- ID
- ZDB-GENE-040426-2903
- Name
- F-box and WD repeat domain containing 11b
- Symbol
- fbxw11b Nomenclature History
- Previous Names
-
- btrc2
- fbxw11
- wu:fa12e12
- wu:fb11f03
- zgc:63728
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have snoRNA binding activity. Involved in sprouting angiogenesis. Predicted to localize to Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Orthologous to several human genes including FBXW11 (F-box and WD repeat domain containing 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63728 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental, jaw, eye, and digital syndrome | 618914 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Domain | IPR001810 | F-box domain |
| Domain | IPR021977 | D domain of beta-TrCP |
| Family | IPR050995 | WD repeat and F-box domain-containing protein |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036047 | F-box-like domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
| Repeat | IPR020472 | G-protein beta WD-40 repeat |
Domain Details Per Protein
| Protein | Length | D domain of beta-TrCP | F-box domain | F-box-like domain superfamily | G-protein beta WD-40 repeat | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily | WD repeat and F-box domain-containing protein |
|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E9QCK5
|
524 | |||||||||
|
UniProtKB:A0A2R8RWN9
|
534 | |||||||||
|
UniProtKB:F6PB05
|
531 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fbxw11b-201
(1)
|
Ensembl | 2,503 nt | ||
| mRNA |
fbxw11b-202
(1)
|
Ensembl | 2,496 nt | ||
| mRNA |
fbxw11b-204
(1)
|
Ensembl | 2,502 nt | ||
| ncRNA |
fbxw11b-002
(1)
|
Ensembl | 765 nt |
Interactions and Pathways
No data available
Plasmids
No data available