Gene

eif3i

ID

ZDB-GENE-040426-1922

Name

eukaryotic translation initiation factor 3, subunit I

Symbol

eif3i Nomenclature History

Previous Names

eif3s2
hm:zehn0464
wu:fb62b08
zgc:56211 (1)
zgc:77823 (1)

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to enable RNA binding activity and translation initiation factor activity. Acts upstream of or within liver development and sprouting angiogenesis. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3m. Is expressed in several structures, including digestive system; endothelial cell; nervous system; otic vesicle; and pectoral fin. Orthologous to human EIF3I (eukaryotic translation initiation factor 3 subunit I).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56211 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Yuan et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eif3i Human Ortholog

No data available

Associated With eif3i Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR024977	Anaphase-promoting complex subunit 4-like, WD40 domain
Family	IPR027525	Eukaryotic translation initiation factor 3 subunit I
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat

Domain Details Per Protein

Protein	Length	Anaphase-promoting complex subunit 4-like, WD40 domain	Eukaryotic translation initiation factor 3 subunit I	WD40 repeat	WD40 repeat, conserved site	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q7ZV55 InterPro	325

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	eif3i-201 (1) Ensembl	Ensembl	1,305 nt	Select Tool ZFIN BLAST
ncRNA	eif3i-002 (1) Ensembl	Ensembl	729 nt	Select Tool ZFIN BLAST
ncRNA	eif3i-003 (1) Ensembl	Ensembl	1,334 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations