ZFIN is now using GRCz12tu for Genomic Data
Gene
pigb
- ID
- ZDB-GENE-040426-1216
- Name
- phosphatidylinositol glycan anchor biosynthesis, class B
- Symbol
- pigb Nomenclature History
- Previous Names
-
- zgc:63658 (1)
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable alpha-1,2-mannosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in acrofrontofacionasal dysostosis 1 and developmental and epileptic encephalopathy 80. Orthologous to human PIGB (phosphatidylinositol glycan anchor biosynthesis class B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63658 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| acrofrontofacionasal dysostosis 1 | Alliance | Acrofrontofacionasal dysplasia 1 | 201180 |
| developmental and epileptic encephalopathy 80 | Alliance | Developmental and epileptic encephalopathy 80 | 618580 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR005599 | GPI mannosyltransferase |
Domain Details Per Protein
| Protein | Additional Resources | Length | GPI mannosyltransferase |
|---|---|---|---|
| UniProtKB:Q7SXZ1 | InterPro | 536 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers