Gene
npl
- ID
- ZDB-GENE-030131-926
- Name
- N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
- Symbol
- npl Nomenclature History
- Previous Names
-
- wu:fb53b06
- zgc:76930
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Description
- Predicted to have N-acetylneuraminate lyase activity. Predicted to be involved in N-acetylneuraminate catabolic process and carbohydrate metabolic process. Predicted to localize to cytoplasm. Used to study myopathy. Is expressed in several structures, including fin bud; gut; muscle; vein; and yolk syncytial layer. Orthologous to human NPL (N-acetylneuraminate pyruvate lyase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 9 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6894589 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- 5 figures from Wen et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| myopathy | WT + MO1-npl | control | Wen et al., 2018 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Aldolase-type TIM barrel | DapA-like | Schiff base-forming aldolase, conserved site |
|---|---|---|---|---|
|
UniProtKB:A9C3P6
|
307 | |||
|
UniProtKB:Q6NYR8
|
307 |
Interactions and Pathways
No data available
Plasmids
No data available