Gene
uqcc2
- ID
- ZDB-GENE-040426-1726
- Name
- ubiquinol-cytochrome c reductase complex assembly factor 2
- Symbol
- uqcc2 Nomenclature History
- Previous Names
-
- zgc:73238
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to be involved in several processes, including mitochondrial respiratory chain complex III assembly; positive regulation of cellular protein metabolic process; and regulation of insulin secretion. Predicted to localize to mitochondrial inner membrane; mitochondrial intermembrane space; and mitochondrial nucleoid. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency nuclear type 7. Is expressed in intestinal bulb; intestinal bulb primordium; liver; and pectoral fin musculature. Orthologous to human UQCC2 (ubiquinol-cytochrome c reductase complex assembly factor 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:73238 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex III deficiency nuclear type 7 | Alliance | Mitochondrial complex III deficiency, nuclear type 7 | 615824 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Complex III assembly factor UQCC2/CBP6 | Ubiquinol-cytochrome-c reductase complex assembly factor 2 |
|---|---|---|---|
|
UniProtKB:Q6PBU7
|
129 |
Interactions and Pathways
No data available
Plasmids
No data available