ZFIN

ZFIN ID: ZDB-MRPHLNO-080814-1

CITATIONS (17 total)

Morpholino Name:	MO1-pdx1
Morpholino Symbol:	MO1-pdx1

Al-Dahmani, Z.M., Li, X., Wiggenhauser, L.M., Ott, H., Kruithof, P.D., Lunev, S., A Batista, F., Luo, Y., Dolga, A.M., Morton, N.M., Groves, M.R., Kroll, J., van Goor, H. (2022) Thiosulfate sulfurtransferase prevents hyperglycemic damage to the zebrafish pronephros in an experimental model for diabetes. Scientific Reports. 12:12077

Wiggenhauser, L.M., Metzger, L., Bennewitz, K., Soleymani, S., Boger, M., Tabler, C.T., Hausser, I., Sticht, C., Wohlfart, P., Volk, N., Heidenreich, E., Buettner, M., Hammes, H.P., Kroll, J. (2022) pdx1 Knockout Leads to a Diabetic Nephropathy-Like Phenotype in Zebrafish and Identifies Phosphatidylethanolamine as Metabolite Promoting Early Diabetic Kidney Damage. Diabetes. 71(5):1073-1080

Lou, B., Boger, M., Bennewitz, K., Sticht, C., Kopf, S., Morgenstern, J., Fleming, T., Hell, R., Yuan, Z., Nawroth, P.P., Kroll, J. (2020) Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans. Redox Biology. 37:101723

Wiggenhauser, L.M., Qi, H., Stoll, S.J., Metzger, L., Bennewitz, K., Poschet, G., Krenning, G., Hillebrands, J.L., Hammes, H.P., Kroll, J. (2020) Activation of retinal angiogenesis in hyperglycemic pdx1^-/- zebrafish mutants. Diabetes. 69(5):1020-1031

Schmöhl, F., Peters, V., Schmitt, C.P., Poschet, G., Büttner, M., Li, X., Weigand, T., Poth, T., Volk, N., Morgenstern, J., Fleming, T., Nawroth, P.P., Kroll, J. (2019) CNDP1 knockout in zebrafish alters the amino acid metabolism, restrains weight gain, but does not protect from diabetic complications. Cellular and molecular life sciences : CMLS. 76(22):4551-4568

Gao, C., Huang, W., Gao, Y., Jan Lo, L., Luo, L., Huang, H., Chen, J., Peng, J. (2018) Zebrafish hhex-null mutant develops an intrahepatic intestinal tube due to de-repression of cdx1b and pdx1. Journal of molecular cell biology. 11(6):448-462

Zhang, Y.M., Zimmer, M.A., Guardia, T., Callahan, S.J., Mondal, C., Di Martino, J., Takagi, T., Fennell, M., Garippa, R., Campbell, N.R., Bravo-Cordero, J.J., White, R.M. (2018) Distant Insulin Signaling Regulates Vertebrate Pigmentation through the Sheddase Bace2. Developmental Cell. 45(5):580-594.e7

She, J., Yuan, Z., Wu, Y., Chen, J., Kroll, J. (2017) Targeting erythropoietin protects against proteinuria in type 2 diabetic patients and in zebrafish. Molecular metabolism. 8:189-202

O'Hare, E.A., Yerges-Armstrong, L.M., Perry, J.A., Shuldiner, A.R., Zaghloul, N.A. (2016) Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of β-Cell Mass Deficits. Molecular endocrinology (Baltimore, Md.). 30(4):429-45

Sharma, K.R., Heckler, K., Stoll, S.J., Hillebrands, J.L., Kynast, K., Herpel, E., Porubsky, S., Elger, M., Hadaschik, B., Bieback, K., Hammes, H.P., Nawroth, P.P., Kroll, J. (2016) ELMO1 protects renal structure and ultrafiltration in kidney development and under diabetic conditions. Scientific Reports. 6:37172

Jörgens, K., Stoll, S.J., Pohl, J., Fleming, T.H., Sticht, C., Nawroth, P.P., Hammes, H.P., Kroll, J. (2015) High tissue glucose alters intersomitic blood vessels in zebrafish via methylglyoxal targeting the VEGF receptor signalling cascade. Diabetes. 64(1):213-25

Yamazoe, S., McQuade, L.E., Chen, J.K. (2014) Nitroreductase-Activatable Morpholino Oligonucleotides for in Vivo Gene Silencing. ACS Chemical Biology. 9(9):1985-90

Jurczyk, A., Roy, N., Bajwa, R., Gut, P., Lipson, K., Yang, C., Covassin, L., Racki, W.J., Rossini, A.A., Phillips, N., Stainier, D.Y., Greiner, D.L., Brehm, M.A., Bortell, R., and diIorio, P. (2011) Dynamic glucoregulation and mammalian-like responses to metabolic and developmental disruption in zebrafish. General and comparative endocrinology. 170(2):334-345

Kimmel, R.A., Onder, L., Wilfinger, A., Ellertsdottir, E., and Meyer, D. (2011) Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish. BMC Biology. 9(1):75

Lin, J.W., Biankin, A.V., Horb, M.E., Ghosh, B., Prasad, N.B., Yee, N.S., Pack, M.A., and Leach, S.D. (2004) Differential requirement for ptf1a in endocrine and exocrine lineages of developing zebrafish pancreas. Developmental Biology. 270(2):474-486

Huang, H., Liu, N., and Lin, S. (2001) Pdx-1 knockdown reduces insulin promoter activity in zebrafish. Genesis (New York, N.Y. : 2000). 30(3):134-136

Yee, N.S., Yusuff, S., and Pack, M. (2001) Zebrafish pdx1 morphant displays defects in pancreas development and digestive organ chirality, and potentially identifies a multipotent pancreas progenitor cell. Genesis (New York, N.Y. : 2000). 30(3):137-140