ZFIN

ZFIN ID: ZDB-GENE-060126-7

ZFIN ID: ZDB-GENE-060126-7

CITATIONS (49 total)

Gene Name:	aryl hydrocarbon receptor nuclear translocator
Gene Symbol:	arnt

Chen, F., Pu, S., Tian, L., Zhang, H., Zhou, H., Yan, Y., Hu, X., Wu, Q., Chen, X., Cheng, S.H., Xu, S. (2024) Radix Rehmanniae Praeparata promoted zebrafish fin regeneration through aryl hydrocarbon receptor-dependent autophagy. Journal of ethnopharmacology. 331:118272

Edwards, H.E., Edgington, M.J., Souder, J.P., Gorelick, D.A. (2023) Hemato-vascular specification requires arnt1 and arnt2 genes in zebrafish embryos. Development (Cambridge, England). 150(9)

Jia, P.P., Chandrajith, R., Junaid, M., Li, T.Y., Li, Y.Z., Wei, X.Y., Liu, L., Pei, D.S. (2023) Elucidating environmental factors and their combined effects on CKDu in Sri Lanka using zebrafish. Environmental pollution (Barking, Essex : 1987). 332:121967

Houseright, R.A., Miskolci, V., Mulvaney, O., Bortnov, V., Mosher, D.F., Rindy, J., Bennin, D.A., Huttenlocher, A. (2021) Myeloid-derived growth factor regulates neutrophil motility in interstitial tissue damage. The Journal of cell biology. 220(8):

Navarrete, J., Wilson, P., Allsing, N., Gordon, C., Margolis, R., Schwartz, A.V., Cho, C., Rogowski, B., Topps, J., George, U.Z., Sant, K.E. (2021) The ecotoxicological contaminant tris(4-chlorophenyl)methanol (TCPMOH) impacts embryonic development in zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 235:105815

Blanc, M., Alfonso, S., Bégout, M.L., Barrachina, C., Hyötyläinen, T., Keiter, S.H., Cousin, X. (2020) An environmentally relevant mixture of polychlorinated biphenyls (PCBs) and polybrominated diphenylethers (PBDEs) disrupts mitochondrial function, lipid metabolism and neurotransmission in the brain of exposed zebrafish and their unexposed F2 offspring. The Science of the total environment. 754:142097

Gu, Q., Ali, S.F., Kanungo, J. (2020) Effects of acetyl L-carnitine on zebrafish embryos: Phenotypic and gene expression studies. Journal of applied toxicology : JAT. 41(2):256-264

Marchi, D., Santhakumar, K., Markham, E., Li, N., Storbeck, K.H., Krone, N., Cunliffe, V.T., van Eeden, F.J.M. (2020) Bidirectional crosstalk between Hypoxia-Inducible Factor and glucocorticoid signalling in zebrafish larvae. PLoS Genetics. 16:e1008757

Nijoukubo, D., Adachi, H., Kitazawa, T., Teraoka, H. (2020) Blood vessels are primary targets for 2,3,7,8-tetrachlorodibenzo-p-dioxin in pre-cardiac edema formation in larval zebrafish. Chemosphere. 254:126808

Guerrero-Castilla, A., Olivero-Verbel, J., Sandoval, I.T., Jones, D.A. (2019) Toxic effects of a methanolic coal dust extract on fish early life stage. Chemosphere. 227:100-108

Jeong, J., Kim, K.H., Kim, D.Y., Chandrasekaran, G., Kim, M., Pagire, S.H., Dighe, M., Choi, E.Y., Bak, S.M., Kim, E.Y., Shin, M.G., Choi, S.Y., Ahn, J.H. (2019) Identification of new aryl hydrocarbon receptor (AhR) antagonists using a zebrafish model. Bioorganic & Medicinal Chemistry. 27(19):115014

Luo, J.J., Su, D.S., Xie, S.L., Liu, Y., Liu, P., Yang, X.J., Pei, D.S. (2018) Hypersensitive assessment of aryl hydrocarbon receptor transcriptional activity using a novel truncated cyp1a promoter in zebrafish. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32(5):2814-2826

Meyer-Alert, H., Ladermann, K., Larsson, M., Schiwy, S., Hollert, H., Keiter, S.H. (2018) A temporal high-resolution investigation of the Ah-receptor pathway during early development of zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands). 204:117-129

Zhang, R., Wang, X., Zhang, X., Song, C., Letcher, R.J., Liu, C. (2018) Polychlorinated Diphenylsulfides Activate Aryl Hydrocarbon Receptor 2 in Zebrafish Embryos: Potential Mechanism of Developmental Toxicity. Environmental science & technology. 52(7):4402-4412

Vettori, A., Greenald, D., Wilson, G.K., Peron, M., Facchinello, N., Markham, E., Sinnakaruppan, M., Matthews, L.C., McKeating, J.A., Argenton, F., van Eeden, F.J.M. (2017) Glucocorticoids promote Von Hippel Lindau degradation and Hif-1α stabilization. Proceedings of the National Academy of Sciences of the United States of America. 114(37):9948-9953

Teraoka, H., Okuno, Y., Nijoukubo, D., Yamakoshi, A., Peterson, R.E., Stegeman, J.J., Kitazawa, T., Hiraga, T., Kubota, A. (2014) Involvement of COX2-thromboxane pathway in TCDD-induced precardiac edema in developing zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 154C:19-26

Thompson, A.A., Elks, P.M., Marriott, H.M., Eamsamarng, S., Higgins, K.R., Lewis, A., Williams, L., Parmar, S., Shaw, G., McGrath, E.E., Formenti, F., Van Eeden, F.J., Kinnula, V.L., Pugh, C.W., Sabroe, I., Dockrell, D.H., Chilvers, E.R., Robbins, P.A., Percy, M.J., Simon, M.C., Johnson, R.S., Renshaw, S.A., Whyte, M.K., and Walmsley, S.R. (2014) Hypoxia-inducible factor 2α regulates key neutrophil functions in humans, mice, and zebrafish. Blood. 123(3):366-76

Fraccalvieri, D., Soshilov, A.A., Karchner, S.I., Franks, D.G., Pandini, A., Bonati, L., Hahn, M.E., and Denison, M.S. (2013) Comparative Analysis of Homology Models of the Ah Receptor Ligand Binding Domain: Verification of Structure–Function Predictions by Site-Directed Mutagenesis of a Nonfunctional Receptor. Biochemistry. 52(4):714-725

Varshney, G.K., Lu, J., Gildea, D., Huang, H., Pei, W., Yang, Z., Huang, S.C., Schoenfeld, D.S., Pho, N., Casero, D., Hirase, T., Mosbrook-Davis, D.M., Zhang, S., Jao, L.E., Zhang, B., Woods, I.G., Zimmerman, S., Schier, A.F., Wolfsberg, T., Pellegrini, M., Burgess, S.M., and Lin, S. (2013) A large-scale zebrafish gene knockout resource for the genome-wide study of gene function. Genome research. 23(4):727-735

Elks, P.M., van Eeden, F.J., Dixon, G., Wang, X., Reyes-Aldasoro, C.C., Ingham, P.W., Whyte, M.K., Walmsley, S.R., and Renshaw, S.A. (2011) Activation of hypoxia-inducible factor-1α (Hif-1α) delays inflammation resolution by reducing neutrophil apoptosis and reverse migration in a zebrafish inflammation model. Blood. 118(3):712-22

Li, I.C., Chan, C.T., Lu, Y.F., Wu, Y.T., Chen, Y.C., Li, G.B., Lin, C.Y., and Hwang, S.P. (2011) Zebrafish krüppel-like factor 4a represses intestinal cell proliferation and promotes differentiation of intestinal cell lineages. PLoS One. 6(6):e20974

Teraoka, H., Ogawa, A., Kubota, A., Stegeman, J.J., Peterson, R.E., and Hiraga, T. (2010) Malformation of certain brain blood vessels caused by TCDD activation of Ahr2/Arnt1 signaling in developing zebrafish. Aquatic toxicology (Amsterdam, Netherlands). 99(2):241-247

Wang, Y., Chen, K., Yao, Q., Zheng, X., and Yang, Z. (2009) Phylogenetic Analysis of Zebrafish Basic Helix-Loop-Helix Transcription Factors. Journal of molecular evolution. 68(6):629-640

Wang, D., Jao, L.E., Zheng, N., Dolan, K., Ivey, J., Zonies, S., Wu, X., Wu, K., Yang, H., Meng, Q., Zhu, Z., Zhang, B., Lin, S., and Burgess, S.M. (2007) Efficient genome-wide mutagenesis of zebrafish genes by retroviral insertions. Proceedings of the National Academy of Sciences of the United States of America. 104(30):12428-12433

Antkiewicz, D.S., Peterson, R.E., and Heideman, W. (2006) Blocking Expression of AHR2 and ARNT1 in Zebrafish Larvae Protects Against Cardiac Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Toxicological sciences : an official journal of the Society of Toxicology. 94(1):175-182

Carney, S.A., Prasch, A.L., Heideman, W., and Peterson, R.E. (2006) Understanding dioxin developmental toxicity using the zebrafish model. Birth defects research. Part A, Clinical and molecular teratology. 76(1):7-18

Mathew, L.K., Andreasen, E.A., and Tanguay, R.L. (2006) AHR Activation Inhibits Regenerative Growth. Molecular pharmacology. 69(1):257-265

Prasch, A.L., Tanguay, R.L., Mehta, V., Heideman, W., and Peterson, R.E. (2006) Identification of Zebrafish ARNT1 Homologs: 2,3,7,8-Tetrachlorodibenzo-p-dioxin Toxicity in the Developing Zebrafish Requires ARNT1. Molecular pharmacology. 69(3):776-787

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

Additional Citations (20):

Zebrafish Nomenclature Committee (2023) Nomenclature Data Curation (2023). Nomenclature Committee Submission.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Burgess, S., and Lin, S. (2012) Viral Insertion Mutants Overwrite Data. ZFIN Direct Data Submission.

Burgess, S., and Lin, S. (2011) Viral Insertion Mutants. ZFIN Direct Data Submission.

UniProt-GOA (2011) Gene Ontology annotation based on the automatic assignment of UniProtKB Subcellular Location terms in UniProtKB/TrEMBL entries. Manually curated data.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

ZFIN Staff (2004) ZGC Data Curation and Association in ZFIN by ZFIN Staff. Semi-automated Curation.

ZFIN Staff (2004) Temporary Manual Curation. Manually curated data.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2003) Curation of orthology data. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.