ZFIN

Phenotype Figure Summary

Marker:	pnpla2
Conditions:	Standard or Control

Publication	Data	Fish	Anatomy
Han et al., 2021	Fig. 1	pnpla2^ecn8/ecn8 (AB)	liver fatty, abnormal liver vacuolated, abnormal liver vacuole increased amount, abnormal liver white, abnormal swimming decreased linear velocity, abnormal whole organism decreased weight, abnormal whole organism docosahexaenoic acid decreased amount, abnormal whole organism elaidic acid increased amount, abnormal whole organism gamma-linolenic acid increased amount, abnormal whole organism hexadecenoic acid increased amount, abnormal whole organism icosenoic acid decreased amount, abnormal whole organism lipid increased amount, abnormal whole organism oxygen metabolic process decreased magnitude, abnormal whole organism phosphatidylcholine decreased amount, abnormal whole organism phosphatidylethanolamine decreased amount, abnormal whole organism protein decreased amount, abnormal whole organism tetracosenoic acid decreased amount, abnormal whole organism triglyceride increased amount, abnormal
	Fig. 4	pnpla2^ecn8/ecn8 (AB)	hepatocyte lipid droplet increased size, abnormal whole organism decreased weight, abnormal whole organism lipid increased amount, abnormal whole organism triglyceride increased amount, abnormal
	Fig. 5	pnpla2^ecn8/ecn8 (AB)	liver abhd5a expression increased amount, abnormal liver atg12 expression decreased amount, abnormal liver atg4a expression decreased amount, abnormal liver atg7 expression decreased amount, abnormal liver becn1 expression decreased amount, abnormal liver fabp10a expression decreased amount, abnormal liver lipea expression decreased amount, abnormal liver lipea expression increased amount, abnormal liver lipeb expression decreased amount, abnormal liver map1lc3b expression decreased amount, abnormal liver mgll expression decreased amount, abnormal liver plin2 expression decreased amount, abnormal liver pnpla2 expression decreased amount, abnormal liver ulk1b expression decreased amount, abnormal
	Fig. 8	pnpla2^ecn8/ecn8 (AB)	liver hspa5 expression increased amount, abnormal liver il6 expression increased amount, abnormal