Gene
pnpla2
- ID
- ZDB-GENE-120913-3
- Name
- patatin-like phospholipase domain containing 2
- Symbol
- pnpla2 Nomenclature History
- Previous Names
-
- atgl (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to enable triacylglycerol lipase activity. Predicted to be involved in lipid homeostasis and triglyceride catabolic process. Predicted to be active in cytoplasm; lipid droplet; and membrane. Is expressed in female organism; liver; and male organism. Orthologous to human PNPLA2 (patatin like phospholipase domain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Han et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neutral lipid storage disease with myopathy | 610717 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Acyl transferase/acyl hydrolase/lysophospholipase | Patatin-like phospholipase domain | Patatin-like phospholipase domain-containing protein | Patatin-like phospholipase domain-containing protein 2 |
|---|---|---|---|---|---|---|
| UniProtKB:E7FGN6 | InterPro |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pnpla2-201
(1)
|
Ensembl | 2,935 nt |
Interactions and Pathways
No data available
Plasmids
No data available