Gene
pnpla2
- ID
- ZDB-GENE-120913-3
- Name
- patatin-like phospholipase domain containing 2
- Symbol
- pnpla2 Nomenclature History
- Previous Names
-
- atgl (1)
- Type
- protein_coding_gene
- Location
- Chr: 25 Mapping Details/Browsers
- Description
- Predicted to have triglyceride lipase activity. Predicted to be involved in lipid catabolic process and positive regulation of triglyceride catabolic process. Is expressed in liver and male organism. Orthologous to human PNPLA2 (patatin like phospholipase domain containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Han et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neutral lipid storage disease with myopathy | 610717 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Acyl transferase/acyl hydrolase/lysophospholipase | Patatin-like phospholipase domain | Patatin-like phospholipase domain-containing protein | Patatin-like phospholipase domain-containing protein 2 |
|---|---|---|---|---|---|
|
UniProtKB:E7FGN6
|
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
pnpla2-201
(1)
|
Ensembl | 2,935 nt |
Interactions and Pathways
No data available
Plasmids
No data available