Publication	Data		Fish	Anatomy
Aman et al., 2021	Fig. 4		dio2vp42rc1/vp42rc1; b1212Tg	scale EGFP expression spatial pattern, abnormal scale increased amount, abnormal scale negative regulation of dermatome development onset quality, abnormal scale primordium EGFP expression spatial pattern, abnormal
Houbrechts et al., 2019	Fig. 1		dio2lv1/lv1 (AB) ,   dio2lv2/lv2 (AB)	male organism increased concentration blood glucose, abnormal
	Fig. 2		dio2lv1/lv1 (AB) ,   dio2lv2/lv2 (AB)	male organism digestive system gcgra expression increased amount, abnormal male organism digestive system gcgrb expression increased amount, abnormal male organism digestive system ins expression increased amount, abnormal
	Fig. 3		dio2lv1/lv1 (AB)	male organism has extra parts of type pancreas glucagon secreting cell, abnormal male organism has extra parts of type pancreas insulin secreting cell, abnormal male organism primary islet increased size, abnormal
	Fig. 4		dio2lv1/lv1 (AB) ,   dio2lv2/lv2 (AB)	male organism digestive system gcgra expression decreased amount, abnormal male organism digestive system gcgrb expression decreased amount, abnormal male organism skeletal muscle gcgrb expression decreased amount, abnormal male organism skeletal muscle insra expression decreased amount, abnormal
	Fig. 5		dio2lv2/lv2 (AB)	male organism digestive system slc2a12 expression decreased amount, abnormal male organism digestive system slc2a2 expression decreased amount, abnormal
	Fig. 6		dio2lv1/lv1 (AB) ,   dio2lv2/lv2 (AB)	male organism digestive system g6pc1a.1 expression decreased amount, abnormal male organism digestive system gys2 expression decreased amount, abnormal male organism digestive system gys2 expression increased amount, abnormal male organism increased concentration liver glycogen, abnormal male organism skeletal muscle hk1 expression decreased amount, abnormal male organism skeletal muscle pkmb expression decreased amount, abnormal
	Fig. 7		dio2lv1/lv1 (AB)	male organism energy homeostasis process efficacy, abnormal
Houbrechts et al., 2019	Fig. 1		dio2lv1/lv1	ovary 3,3',5-triiodo-L-thyronine decreased amount, abnormal ovary dio1 expression increased amount, abnormal ovary thraa expression increased amount, abnormal testis 3,3',5-triiodo-L-thyronine decreased amount, abnormal testis dio1 expression decreased amount, abnormal testis thrb expression decreased amount, abnormal
	Fig. 2		dio2lv1/lv1	whole organism decreased fecundity, abnormal whole organism decreased female fertility, abnormal whole organism decreased male fertility, abnormal
	Fig. 3		dio2lv1/lv1	oocyte stage I increased amount, abnormal oocyte stage III decreased amount, abnormal ovary increased size, abnormal testis altered number of sperm, abnormal testis altered number of spermatogonium, abnormal
	Fig. 4		dio2lv1/lv1	oocyte stage I increased amount, abnormal oocyte stage III decreased amount, abnormal ovary increased size, abnormal testis altered number of sperm, abnormal testis altered number of spermatogonium, abnormal
	Fig. 5		dio2lv1/lv1	female organism liver vtg1 expression increased amount, abnormal male organism brain kiss2 expression increased amount, abnormal ovary igf3 expression increased amount, abnormal testis igf3 expression increased amount, abnormal
	Fig. 6		dio2lv1/lv1	ovary ar expression increased amount, abnormal ovary esr2b expression increased amount, abnormal ovary hsd11b2 expression decreased amount, abnormal ovary estradiol decreased amount, abnormal testis 11-Ketoandrosterone decreased amount, abnormal testis ar expression increased amount, abnormal testis hsd11b2 expression decreased amount, abnormal testis hsd17b3 expression increased amount, abnormal testis testosterone decreased amount, abnormal urine 11-Ketoandrosterone decreased amount, abnormal urine estradiol decreased amount, abnormal
	Fig. 7		dio2lv1/lv1	reproductive senescence premature, abnormal sexual reproduction delayed, abnormal whole organism decreased fecundity, abnormal whole organism decreased female fertility, abnormal whole organism decreased male fertility, abnormal
Houbrechts et al., 2016	Fig. 2		dio2lv1/lv1 ,   dio2lv2/lv2	hypophysis tshba expression increased amount, abnormal liver dio2 expression absent, abnormal thyroxine 5'-deiodinase activity decreased process quality, abnormal thyroxine 5'-deiodinase activity disrupted, abnormal
	Fig. 3		dio2lv1/lv1	brain dio3a expression decreased amount, abnormal brain dio3b expression decreased amount, abnormal brain thraa expression decreased amount, abnormal heart dio2 expression increased amount, abnormal liver dio2 expression increased amount, abnormal liver dio3a expression decreased amount, abnormal liver dio3b expression decreased amount, abnormal liver igfbp1a expression decreased amount, abnormal liver thrb expression decreased amount, abnormal skeletal muscle dio1 expression decreased amount, abnormal skeletal muscle dio2 expression increased amount, abnormal skeletal muscle dio3b expression decreased amount, abnormal skeletal muscle mylpfa expression decreased amount, abnormal
	Fig. 4		dio2lv1/lv1 ,   dio2lv2/lv2	locomotion process quality, abnormal swim bladder decreased functionality, abnormal swim bladder inflation disrupted, abnormal swim bladder non-functional, abnormal whole organism dead, abnormal whole organism decreased mobility, abnormal
	Fig. 5		dio2lv1/lv1	barbel absent, abnormal embryo development delayed, abnormal swim bladder inflation disrupted, abnormal whole organism decreased size, abnormal
	Fig. 6		dio2lv1/lv1 ,   dio2lv2/lv2	embryo development delayed, abnormal eye decreased size, abnormal inner ear decreased size, abnormal whole organism decreased length, abnormal
	Fig. 7		dio2lv1/lv1 ,   dio2lv2/lv2	whole organism decreased length, abnormal
	Table 2		dio2lv1/lv1 ,   dio2lv2/lv2	egg-laying behavior disrupted, abnormal whole organism decreased female fertility, abnormal whole organism decreased male fertility, abnormal
Bohnsack et al., 2013	Fig. S4		WT + MO1-dio2	retina tyr expression decreased amount, abnormal
Walpita et al., 2010	Fig. 1		WIK + MO1-dio2	embryonic morphogenesis paedomorphic growth, abnormal whole organism hypoplastic, abnormal
	Fig. 2		WIK + MO1-dio2	developmental pigmentation disrupted, abnormal head orientation trunk, abnormal inner ear hypoplastic, abnormal whole organism decreased pigmentation, abnormal
Walpita et al., 2009	Fig. 3		WIK + MO1-dio2	developmental pigmentation delayed, abnormal embryo development delayed, abnormal
	Fig. 4		WIK + MO1-dio2 ,   WIK + MO2-dio2	developmental pigmentation delayed, abnormal embryo development delayed, abnormal