Genomic Feature
ibl55
- ID
- ZDB-ALT-220331-17
- Name
- ibl55
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Spaink Lab
- Current Source
- Other Pages
-
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 4: 19032042 - 19032049 (GRCz11) (1) Details
- Nucleotide change
- TAGAGGGC/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 8 bp deleted in Exon 2 (1)
- Transcript Consequence
- Frameshift (1)
- Protein Consequence
- None
- Flanking Sequence
-
AACAAGAAAAGACAGTATAGGCCACTGATTTTTGTAAACATAATTTATTTTAAAAATCTTAAAAAAACAAAAGTGCATACAATCTTTACAATCCTTCTTCTTACAGTATATAACACATATTATAACACAATCCACAACTACAGGCAAGTTGGAATTATCAGTGCTATGTTGTAATATCAAAAATATAGCTTAGAAAATAGAAAGCTGCAGCACTAACATAAAAACTGAGAACTAAACAAGTGAAATAAGTTAAATAATTTAGAGAACTAGTCCTTGCATGTGCCATTGTGTTTTAAAAGTGATGCATAGAAGTAACAATGCATGGCTTACACATTTCAGAGAATGAATGTCTCAGCCACATCTGTATCTTTGCAGTATTTCAGTTTGTCTATGTTGAGGCAGAGCTTCTCCAGGAACCTCTGGAGCTCCAGGAGGTGCAGGTAGTTGGAGGTGACGGGGAAGGCTGTTTCTTCTTTATGCACCGGGGTCTCGGGATTGGG
TAGAGGGC/- ATCCCTGTGAGACGGCCAGTTCCTCCAGTGTCCTCAGGAGAGTCTCTAAGTCTATCTGGACCTGCTGTAGGTGCTGAGCTGGAGGAACATGCAACCGCAACTGCAGGTAACTCAAGTAACTCAAGACAGAACTGAGACCATCAATGGGGTTGTCGATGTCAGGGCCGAAATCAATCTCTGGAGACATCTGGAAGTGCTAGAGAGATATGCAGATGTTACTGATTGTAATTGTTATGTGTTTTTATATGTAGTTGACGTTCAAACTATTAGTGGAATTTAGTCATTGATCATTCTGCTGTGGTGACTCTTGATAAATCAAGAACTAAGCTGATGGAAAATGAATGAATGAATAAAAAATGTATCATTTAATTAGAAAGGCCAAGAACCAAGAGCCTTTTTTCCCAACATTTTTAAACAACATAGTTTTAAAAACTAATTAGTTTTTGCCATAGAGTTAAAACATATTTTTTTTTTACCTGTTATTTTAGTAGTTATTTATA - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| lepbibl55/ibl55 (AB/TL) | Homozygous | ♀+/- ♂+/- | 4 figures from He et al., 2021 | ||
| lepbibl55/ibl55; s952Tg | Complex |
1 - 2 of 2
Show
Supplemental Information
- Genotyping protocol
- None
- Ding, Y., Haks, M.C., van den Eeden, S.J.F., Ottenhoff, T.H.M., Harms, A.C., Hankemeier, T., Eeza, M.N.H., Matysik, J., Alia, A., Spaink, H.P. (2022) Leptin mutation and mycobacterial infection lead non-synergistically to a similar metabolic syndrome. Metabolomics : Official journal of the Metabolomic Society. 18:67
- He, J., Ding, Y., Nowik, N., Jager, C., H Eeza, M.N., Alia, A., Baelde, H.J., Spaink, H.P. (2021) Leptin deficiency affects glucose homeostasis and results in adiposity in zebrafish. The Journal of endocrinology. 249(2):125-134
1 - 2 of 2
Show