Genomic Feature
fl9
- ID
- ZDB-ALT-181214-5
- Name
- fl9
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one deletion (1)
- Protocol
- embryos treated with
- Lab of Origin
- Fadool Lab
- Current Source
- Other Pages
Notes
No data available
Variants
- Variant Type
- Small Deletion
- Variant Location
- Chr 8: 54076593 - 54076616 (GRCz11) (1) Details
- Nucleotide change
- ACGCCGGAGACACGGAGCTGGAAG/-
- Variant Notes
- None
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- 24 bp deleted (1)
- Transcript Consequence
- Premature Stop (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
ACACTGGTAAGCTCTCATCAGTCATCAGGATCATTTATTCAGGTGTTAATACTAGGTTCACATCACTGACACAGCTCAATCAAAACATAAACAGAGCGATTTAATTTGCAAAGTGCTTTTTATTGTTACGTTGCCTTGAATACATGCCTCTACAATCACAACAAAGCCAGTATAAGGAGTCCAGCAGTAAGAGAGTTAAGATGTGTTTCCTTCTGCTGCGTTTTAGGAGGAGAGAACAGGAAGGATCTTATGCACCGTTACGCTGGACTCGCTGGATGATGTACTGAAACCAGAACAGGGTCTGTCCTCTCTCAAAACTGTCTTTTGGTTGAACCAATTGGGTTTTGTAAAAATACAAAAAGGAAAACTGACAGACATTTTTTTCTGCAAGTGGTAGCGGTCGCTCGTTTCCCTGGGCTGAGCGCTTCGTGGTCTCTGTGTGGTTTGCCGTGGGAGCCCAGTGCAGGTCGCTGCTTCGAGAGTGTCTGGAAGGAGAGTTT
ACGCCGGAGACACGGAGCTGGAAG/- ACACGGACGAAGCCTCGGTCTTGGAGGCGGTGGTGGAGGCGCCCTCTTCCTCTTCGAAGGGGTTCTTGCCGCAGCACAGGGTGGTGATCATGCAGTGACGGAACTGCTTGTTCATGCAGATGTAGATGCAGGGGTTGTAGACGGCGGACGTCTTGGCGAAGAAGGCGGGCAGGGTCATGAAGACGGGCCCGAACTCGCTGCCCTGGTGGGTGAAGATGTACCAGGCCACGCCGGCGTAGGGCAACCAGCAGATGAGGAAGGCGATGACCATGATGATGACCATGCGGGTGACCTCGCGCTCGGCCCGCTGTGTGGTCTCGGACTCCTGCTGCTGCGCTGCCGCCTCCTTCACAGTGCACACCAGCCGGCCATAGCAGAAGAAGATGACTATCAGTGGGATGAAGAAGTGCACGATGAACATGTAGATGACGAAGGACTCGTTGTTGACACCGGGAGTGCGGGTGTAGTAGTCGACGCCGCAGGAGCACTGCATGCCCTCG - Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| rhofl9/+ | Heterozygous | Unknown | Fig. 5  from Zelinka et al., 2018 | 2 figures from Zelinka et al., 2018 | |
| rhofl9 (AB) | Unknown | Unknown | Fig. 3 from Cleghorn et al., 2021 | ||
| rhofl9/+; fl1Tg | Complex | Fig. 4 from Zelinka et al., 2018 |
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Supplemental Information
- Genotyping protocol
- None
- Cleghorn, W.M., Burrell, A.L., Giarmarco, M.M., Brock, D.C., Wang, Y., Chambers, Z.S., Du, J., Kollman, J.M., Brockerhoff, S.E. (2021) A highly conserved zebrafish IMPDH retinal isoform produces the majority of guanine and forms dynamic protein filaments in photoreceptor cells. The Journal of biological chemistry. 298(1):101441
- Zelinka, C.P., Sotolongo-Lopez, M., Fadool, J.M. (2018) Targeted disruption of the endogenous zebrafish rhodopsin locus as models of rapid rod photoreceptor degeneration.. Molecular Vision. 24:587-602
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