Genomic Feature

tsu20

ID
ZDB-ALT-180521-4
Name
tsu20
Synonyms
None
Affected Genomic Region
Construct
None
Type
Allele with one delins (1)
Protocol
embryos treated with
Lab of Origin
Meng Lab
Current Source
China Zebrafish Resource Center (CZRC)    ( order this )
Other Pages
Notes
No data available
Genome Browser
Genome Build: GRCz11Chromosome: 5
Variants
Variant Type
Delins
Variant Location
Chr 5: 61472186 - 61472190 (GRCz11) (1) Details
Nucleotide change
TGTGG/A
Variant Notes
Between 90 bp to 94 bp of the wild-type alkbh4 coding sequence, TGTGG is  ...
the premature stop codon leads to the lack of the catalytic domain of the  ...
Effect on DNA/cDNA, transcript, protein (from publications)
DNA/cDNA Change
1 bp inserted / 5 bp deleted in Exon 3 (1)
Transcript Consequence
Premature Stop (1)
Protein Consequence
None
Sequences
Flanking Sequence
AGTAATGTGGGCTGGTGTGGCTACAGTGCCAGGGCTGATTTAAAGTCCCAGTCCGCCCCTAAACGATGGTTTACTCTGCAGACGATCAGAAAAAAAAGCTTAAAGGGGCTAATAATTTTGTCCCTAAAATGGTATTTAAAAAGTTAAAAACTGCTTTTATTCTAGCCGAAAAAAAAACAAAACAAATAAGACTTTCTCCAGAAGAAAAAATATTTCTGAAGTATATAAGTCCTGAAGAAACTGAAGTATGGGGTGACGTGAACAAAATCATTGATCCATTTAGGTGGAAGTGACAAACTGCAGGCTTTGGATGCTTATATCAGTTTAATATCTTCTAAACCTGGGTTTTATCACGGTTTTGGAGCACACTAGCTTATAGATATTCTTAAAACTAACATACTGATACTAAAAACTAGAAAACCTTTATTTTAATTTCATGAGACATCTGTCTATCCAAAGGACTTTGGGCCAAAGGTGAACTTCAAGAAGCGCCGTGTCCA
TGTGG/A GAAGCTTCAGCGGCCTGCCTGCTATCAGTCGTCGGCTGCTGGTCCGGATGTCAGATTTACCCCAGTTATCTTCGTTCAAACCAGTGGAGCAGTGCAACCTGGACTATGATTCTCTCAGAGGCTCCGCCATCGACCCACACTTAGACGACAGCTGGCTGTGGGGAGAAAACCTGGTCACCGTTAACCTGCTCTCGGACACCGTTCTGACCTTGAGCTTGGATCAGGGCTGGGGAGACATGGAGCAGGGCGAGGTGAGGGTGGCTGTGCGTCTTCCCCGCAGGTCTCTGGTTGTGCTCTACGGAGATGCACGGCACCGGTGGAAACATGCCATCCACAGAAAAGACATTCACGGCCGCAGAGTGTGCAGCACCTTTCGGGAGCTCTCGGCTGAGTTTCTCCCCGGAGGACAGCAGGAGAAACTGGGCTCAGAGTTGTTGGATATAGCGCTGAGCTTCCAGGGTGCTCCTCTATAAGACAGCTCCACTTAGATGCATGTTTGT
Additional Sequence
None
Fish
Fish Genomic Feature Zygosity Parental Zygosity Affected Genomic Regions Phenotype Gene Expression
alkbh4tsu20/tsu20Homozygous♀+/- ♂+/-Fig. 3 with image from Sun et al., 2017
alkbh4tsu20/tsu20Homozygous♀-/- ♂-/-2 figures with image from Sun et al., 2017Fig. 3 with image from Sun et al., 2017
alkbh4tsu20/+Heterozygous♀-/- ♂+/+Fig. 3 with image from Sun et al., 2017
atrntsu22/tsu22; alkbh4tsu20/tsu20ComplexFig. 9 with image from Sun et al., 2017
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Supplemental Information
Genotyping protocol
None
Citations
TSV
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