Genomic Feature
hkz3
- ID
- ZDB-ALT-130204-1
- Name
- hkz3
- Synonyms
- None
- Affected Genomic Region
- Construct
- None
- Type
- Allele with one point mutation (1)
- Protocol
- ENU
- Lab of Origin
- Wen Lab
- Current Source
- Other Pages
- Note
-
Sequencing of the cmyb locus revealed a T-to-A splice mutation leading to a competitive splice acceptor. the cmyb transcript contained a 13 nucleotide insertion between exon 8 and exon 9. This mutation leads to a truncated c-Myb protein lacking the transactivation domain but retains the DNA-binding domain
Variants
- Variant Type
- Point Mutation
- Variant Location
- Chr 23: 31822034 (GRCz11) (1) Details
- Nucleotide change
- T/A
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- T>A in Intron 8 (1)
- Transcript Consequence
- Splicing Variant (1)
- Protein Consequence
- Polypeptide Truncation (1)
- Flanking Sequence
-
TGCAACACATTTATTAAACAGATATTTTTTATGTGAATCCCTCAAAAAATACACGCTTTCATGTCATTTTTCCCATTTATAATCACAATTTGAGCTTAATAAACAAACACTGAATTTACTTTGCTCTCATCTCACATAGAGACACTACAGCGACGAGGACCCCGAAAAAGAAAAGAGGGTGAAAGAAATCGAGATGCTGTTGATGTCAACAGAAAACGAGCTGAAGGGACAACAGGCACTACCAGTAAGTGTGTCTCTCTGTGCGTGTGTGTGTGTGTTTAATTGGAGGAAGCATCTGGGGGTCTATTTCACATGCTTCAACTGCTTGGCTAAATGATGCAATTGCACCTTATCACACCACAAGCTCTGTTTAACTCCTTGTGCAACTGAGAACCCCCTCCCAACCCTTCACATCATTCAACTCGACAAGTTCCCTTTCTCTCTGACCGCTTTTCCTGCATGCATTCCTCTCTTTCTTTCGCTTAATTTTGCTCTTTTTT
T/A GTTCCCCCACCCAGATCTCCATGAACGGCTACGGTGGCTGGAACAGAGGCTCTTTGGCGGACAGTTCGGTTGGCATTGTTGTTTCAGTCCCGGCTCCATCCCTAGAGCAAGGATGCCTTCCTGAAGAAAGCGCACATGGCAACACAAACAGCCCAAATAACGACTCCAGCTCCACTTTACCAGAGTTTATCGATGCTATTGATTCGGTAAGTTCATCTAAAATGAACAGTGACCATGTATTCATCAGCTAGCATCTAGCGTTAAAGGGATAGTTCACTCAAAAACTAAAAATTCTGTCATCATTTACTCACCTTTCACTTGAGTTTCTTTCTCCTATTAAACAAAAGAGAAGGTATTTTGAAGAAAGTTGAAAACTTGTAACCTTTGACTTCCATAGTATTTGATTTCCAACATACTACTCAATGGTTACAGGTTTTCAGCTCATCTTCTTTAGTGTTCAGCAGAAGAAAGAAACTCCTAAGTGTTTTGAAACCACACGA - Additional Sequence
- None
Fish
Supplemental Information
- Genotyping protocol
- None