Genomic Feature

nz15

ID
ZDB-ALT-110914-3
Name
nz15
Synonyms
  • lib (1)
Affected Genomic Region
Construct
None
Type
Allele with one point mutation (1)
Protocol
adult males treated with ENU
Lab of Origin
Davidson Lab
Current Source
Other Pages
Note
Sequence analysis of aldh1a2 transcripts from nz15 mutants detected a C to A transversion at nucleotide 174 that is predicted to introduce a Stop codon in lieu of a Tyrosine residue at amino acid position 58 in the 519 amino acid raldh2 enzyme.
Genome Browser
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Variants
Variant Type
Point Mutation
Variant Location
Chr 7: 30352292 (GRCz11) (1) Details
Nucleotide change
G/T
Variant Notes
Sequence analysis of aldh1a2 transcripts from nz15 mutants detected a C to A  ...
Effect on DNA/cDNA, transcript, protein (from publications)
DNA/cDNA Change
C>A at position 174 (1)
Transcript Consequence
Premature Stop (1)
Protein Consequence
Tyr>Stop at position 58 (1)
Sequences
Flanking Sequence
AATGATATAACATTATCCTCCAAACAGGTGTTTGTCCACCTCAGGGACAAATTAAATCCATTCATTCCGGATGAGTCTCAATGACTTCCCCAGTTGCACGTTCAGGGGGTCTCTATTTCCTGTATCCATTCTGGTTTTCCACACTTTCTGCCTGATTTACAGAGAGGAACTACAGCCTCTAGCTTGCTTAACCACATTAGACTGAACTACAGCCCCTTCCCTCCCTCTCTTTCAGTTCTGGATGCTTATTCATGCTGAGTGAAGGCTGAAAGTGAGAAGCACAATAGCGGCGCTGGACGACTAAATGTAGTCCAGCAGAGCAATTGTGCCAAACCTGTTTCTGGCAATGCTTTGACCAATTACCAAATACACACTCTGCTGACAAACACACTAGCATGCTAAGAAACCACACACGCGCGCACACACACACACACACACACACACAAACAGACCTTGTCGGATTCCTGGACATCACAGATCTTCTCTCCTGTGGCAGGGTT
G/T TACGTGTGGAAGACCTTGCCGCTCACAGAATCATGCCATTCATTATTAATAAAAATCTACAATGAGAGAAAGGAAAGATATTGTTTAGTTTTCACAACAGTTTTAAAGCAACAAGGTGGAAGTTAGGCAGAACTATCTCAGAATTGTAGCTTTGTGTTGTGGAAGGGTTGTCTGAATGTTCTGAACGAAAGTTCTTCCAGTGACATTAAATAAACATTCTGCTTTCTAATGTTCTCAAAATGTTACCACAAAATCATTTCAGCAATTCTTTGATAGAAGTGCTATAAGCAAGAAGACATAAAACTATATTAAAATTTGAAATGCTGAAATGAACAATGCAGCCAATTACAAAAACTTCTATACAAAAAAATATTTTTTATTCTTAATATACAGTGCAATACTGCAAAGAAGATATATATATATATATATATATATATATATATATATATATATATATATATATATATATACATATATATATATATACATATATATATATT
Additional Sequence
None
Fish
Supplemental Information
Genotyping protocol
None
Citations