Genomic Feature
hi1058Tg
- ID
- ZDB-ALT-020430-20
- Name
- hi1058Tg
- Synonyms
-
- hi1058 (1)
- Affected Genomic Region
- Construct
- Type
- Allele caused by Transgenic insertion (1)
- Protocol
- DNA
- Lab of Origin
- Hopkins Lab
- Current Source
- Zebrafish International Resource Center (ZIRC) ( order this )
- Other Pages
Notes
| Comment | Citation |
|---|---|
| The construct was inserted on the minus strand of the genome. The gene in which ... | ZFIN Curated Data |
Variants
- Variant Type
- Transgenic Insertion
- Variant Location
- Chr 6: 40071646 - 40071647 (GRCz11) (1) Details
- Nucleotide change
- Variant Notes
Effect on DNA/cDNA, transcript, protein (from publications)
- DNA/cDNA Change
- Insertion in Intron 1 (1)
- Transcript Consequence
- None
- Protein Consequence
- None
- Flanking Sequence
- None
- Additional Sequence
- None
Fish
| Fish | Genomic Feature Zygosity | Parental Zygosity | Affected Genomic Regions | Phenotype | Gene Expression |
|---|---|---|---|---|---|
| sec61a1ahi1058Tg/hi1058Tg | Homozygous | ♀+/- ♂+/- | 3 figures  from 3 publications | ||
| sec61a1ahi1058Tg/+ (AB) | Heterozygous | Unknown | |||
| sec61a1ahi1058Tg | Unknown | Unknown | Fig. for (hi1058) from Phenotype Annotation (1994-2006) |
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Supplemental Information
- Genotyping protocol
- hi1058tg.pdf
- Doll, C.A., Burkart, J.T., Hope, K.D., Halpern, M.E., and Gamse, J.T. (2011) Subnuclear development of the zebrafish habenular nuclei requires ER translocon function. Developmental Biology. 360(1):44-57
- Nissen, R.M., Amsterdam, A., and Hopkins, N. (2006) A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for Endothelin-1 expression. BMC Developmental Biology. 6:28
- Amsterdam, A., Nissen, R.M., Sun, Z., Swindell, E., Farrington, S., and Hopkins, N. (2004) Identification of 315 genes essential for early zebrafish development. Proceedings of the National Academy of Sciences of the United States of America. 101(35):12792-12797
- Golling, G., Amsterdam, A., Sun, Z., Antonelli, M., Maldonado, E., Chen, W., Burgess, S., Haldi, M., Artzt, K., Farrington, S., Lin, S.Y., Nissen, R.M., and Hopkins, N. (2002) Insertional mutagenesis in zebrafish rapidly identifies genes essential for early vertebrate development. Nature Genetics. 31(2):135-140
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