| ZFIN ID: ZDB-EXP-250128-12 |
Experiment Conditions Description: chemical treatment by environment: plerixafor
| chemical treatment by environment: plerixafor |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | plerixafor |
|---|---|
| Synonyms: | 1,1'-(benzene-1,4-diyldimethanediyl)bis(1,4,8,11-tetraazacyclotetradecane), 1,1'-[1,4-phenylenebis(methylene)]bis(1,4,8,11-tetraazacyclotetradecane), 1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane, AMD 3100, AMD-3100, AMD3100, JKL 169, JM3100, Mozobil, plerixafor, plerixaforum, SDZ SID 791 |
| Definition: | An azamacrocycle consisting of two cyclam rings connected by a 1,4-phenylenebis(methylene) linker. It is a CXCR4 chemokine receptor antagonist and a hematopoietic stem cell mobilizer. It is used in combination with grulocyte-colony stimulating factor (G-CSF) to mobilize hematopoietic stem cells to the perpheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin's lymphoma and multiple myeloma. |
| Ontology: | ChEBI [CHEBI:125354] ( EBI ) |
| Publication: | Ahuja et al., 2024 |
|---|