| ZFIN ID: ZDB-EXP-240903-2 |
Experiment Conditions Description: chemical treatment by diet: simvastatin, high fat
| chemical treatment by diet: simvastatin |
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| Name: | chemical treatment by diet |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the diet. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000239] |
| Name: | simvastatin |
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| Synonyms: | (1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate, 2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one, MK-733, simvastatin, Simvastatina, Simvastatine, Simvastatinum, Zocor |
| Definition: | A member of the class of hexahydronaphthalenes that is lovastatin in which the 2-methylbutyrate ester moiety has been replaced by a 2,2-dimethylbutyrate ester group. It is used as a cholesterol-lowering and anti-cardiovascular disease drug. |
| Ontology: | ChEBI [CHEBI:9150] ( EBI ) |
| high fat |
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| Name: | high fat |
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| Synonyms: | |
| Definition: | Fat content condition in which the amount of fat in the diet is elevated. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000122] |
| Publication: | Hu et al., 2022 |
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