ZFIN ID: ZDB-EXP-240620-1
Experiment Conditions Description: chemical treatment by injection: decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone
chemical treatment by injection: decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone
Name: chemical treatment by injection
Synonyms:
Definition: Chemical treatment in which the chemical is injected into the zebrafish.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000237]
Name: decanoyl-L-Arg-L-Val-L-Lys-L-Arg-chloromethylketone
Synonyms: dec-RVKR-cmk, decanoyl-Arg-Val-Lys-Arg-chloromethylketone, decanoyl-RVKR-CMK, N(2)-(1-oxodecyl)-L-arginyl-L-valyl-N-[(1S)-4-[(aminoiminomethyl)amino]-1-(2-chloroacetyl)butyl]-L-lysinamide, N(2)-decanoyl-L-arginyl-L-valyl-N-[(3S)-6-carbamimidamido-1-chloro-2-oxohexan-3-yl]-L-lysinamide
Definition: A tetrapeptide consisting of N-decanoyl-L-arginine, L-valine, L-lysine, and L-arginine joined in sequence by peptide linkages and in which the carboxy group at the C-terminus is substituted by a chloroacetyl group. It is a furin inhibitor that has antiviral activity against Chikungunya virus, Zika virus and Japanese encephalitis virus.
Ontology: ChEBI [CHEBI:156289]  ( EBI )
Publication: Klaver et al., 2021