| ZFIN ID: ZDB-EXP-240320-2 |
Experiment Conditions Description: hypoxia, chemical treatment by environment: gefitinib
| hypoxia |
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| Name: | hypoxia |
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| Synonyms: | |
| Definition: | An oxygen content with low concentration of oxygen. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000189] |
| chemical treatment by environment: gefitinib |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | gefitinib |
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| Synonyms: | 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline, gefitinib, gefitinibum, Iressa, Irressat, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine, N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine, ZD 1839, ZD-1839, ZD1839 |
| Definition: | A member of the class of quinazolines that is quinazoline which is substituted by a (3-chloro-4-fluorophenyl)nitrilo group, 3-(morpholin-4-yl)propoxy group and a methoxy group at positions 4,6 and 7, respectively. An EGFR kinase inhibitor used for the treatment of non-small cell lung cancer. |
| Ontology: | ChEBI [CHEBI:49668] ( EBI ) |
| Publication: | Heliste et al., 2021 |
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