Search Ontology:
ChEBI
gefitinib
- Term ID
- CHEBI:49668
- Synonyms
-
- 4-(3'-chloro-4'-fluoroanilino)-7-methoxy-6-(3-morpholinopropoxy)quinazoline
- gefitinib
- gefitinibum
- Iressa
- Irressat
- N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-(4-morpholinyl)propoxy)-4-quinazolinamine
- N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
- ZD 1839
- ZD-1839
- ZD1839
- Definition
- A member of the class of quinazolines that is quinazoline which is substituted by a (3-chloro-4-fluorophenyl)nitrilo group, 3-(morpholin-4-yl)propoxy group and a methoxy group at positions 4,6 and 7, respectively. An EGFR kinase inhibitor used for the treatment of non-small cell lung cancer.
- References
-
- CAS:184475-35-2
- DrugBank:DB00317
- Drug_Central:1282
- HMDB:HMDB0014462
- KEGG:D01977
- LINCS:LSM-1098
- PDBeChem:IRE
- PMID:14981586
- PMID:15068398
- PMID:20573926
- PMID:20949670
- PMID:27396387
- PMID:28968167
- PMID:29332330
- PMID:29493460
- PMID:29579334
- PMID:29668619
- PMID:30068310
- PMID:30069771
- PMID:30214852
- Reaxys:8949523
- Wikipedia:Gefitinib
- Ontology
- ChEBI ( EBI )
- is a type of
- has_role
-
- inverse has_functional_parent
-
Phenotype
Phenotype resulting from gefitinib
Phenotype where environments contain gefitinib
Phenotype modified by environments containing gefitinib
Human Disease Model