| ZFIN ID: ZDB-EXP-230712-11 |
Experiment Conditions Description: cryoablation: cardiac ventricle, chemical treatment by injection: clodronic acid
| cryoablation: cardiac ventricle |
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| Name: | cryoablation |
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| Synonyms: | |
| Definition: | Experimental condition which uses a cold instrument to ablate an anatomical structure or cell. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000249] |
| Name: | cardiac ventricle |
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| Synonyms: | ventricle |
| Definition: | Cavitated compound organ that receives blood flow from the atrium and delivers blood to the body via the aorta. Valves are present to direct flow. There are only two chambers present in the fish heart. |
| Ontology: | Anatomy Ontology [ZFA:0000009] |
| chemical treatment by injection: clodronic acid |
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| Name: | chemical treatment by injection |
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| Synonyms: | |
| Definition: | Chemical treatment in which the chemical is injected into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000237] |
| Name: | clodronic acid |
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| Synonyms: | (Dichloro-phosphono-methyl)-phosphonic acid, (dichloromethanediyl)bis(phosphonic acid), (dichloromethylene)bisphosphonic acid, (dichloromethylene)diphosphonic acid, acide clodronique, acido clodronico, acidum clodronicum, clodronate, clodronic acid, clodronsaeure, dichloromethylene-1,1-bisphosphonic acid, dichloromethylene-1,1-diphosphonic acid, dichloromethylidene diphosphonate |
| Definition: | An organochlorine compound that is methylene chloride in which both hydrogens are replaced by phosphonic acid groups. It inhibits bone resorption and soft tissue calcification, and is used (often as the disodium salt tetrahydrate) as an adjunct in the treatment of severe hypercalcaemia associated with malignancy, and in the management of osteolytic lesions and bone pain associated with skeletal metastases. |
| Ontology: | ChEBI [CHEBI:110423] ( EBI ) |
| Publication: | Bevan et al., 2019 |
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