ZFIN ID: ZDB-EXP-220922-5 |
Experiment Conditions Description: chemical treatment by environment: GABA modulator
chemical treatment by environment: GABA modulator |
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Name: | chemical treatment by environment |
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Synonyms: | |
Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
Name: | GABA modulator |
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Synonyms: | GABA modulators |
Definition: | A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act. |
Ontology: | ChEBI [CHEBI:50268] ( EBI ) |
Publication: | Weuring et al., 2020 |
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