Search Ontology:
ChEBI

GABA modulator

Term ID
CHEBI:50268
Synonyms
  • GABA modulators
Definition
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
inverse has_role
Phenotype
Phenotype resulting from GABA modulator
Phenotype where environments contain GABA modulator
Phenotype modified by environments containing GABA modulator
Human Disease / Model Data
Citations