ZFIN ID: ZDB-EXP-210329-3
Experiment Conditions Description: chemical treatment by environment: naloxone, chemical treatment by environment: beta-casomorphin-7 (human)
chemical treatment by environment: naloxone
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: naloxone
Synonyms: (-)-naloxone, 1-N-Allyl-14-hydroxynordihydromorphinone, 17-allyl-3,14-dihydroxy-4,5alpha-epoxymorphinan-6-one, 3,14-dihydroxy-17-(prop-2-en-1-yl)-4,5alpha-epoxymorphinan-6-one, naloxona, naloxone, naloxonum
Definition: A synthetic morphinane alkaloid that is morphinone in which the enone double bond has been reduced to a single bond, the hydrogen at position 14 has been replaced by a hydroxy group, and the methyl group attached to the nitrogen has been replaced by an allyl group. A specific opioid antagonist, it is used (commonly as its hydrochloride salt) to reverse the effects of opioids, both following their use of opioids during surgery and in cases of known or suspected opioid overdose.
Ontology: Chebi [CHEBI:7459]
chemical treatment by environment: beta-casomorphin-7 (human)
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: beta-casomorphin-7 (human)
Synonyms: H-Tyr-Pro-Phe-Val-Glu-Pro-Ile-OH, human beta-casomorphin (1-7), human beta-casomorphin-7, L-Tyr-L-Pro-L-Phe-L-Val-L-Glu-L-Pro-L-Ile, NH2-Tyr-Pro-Phe-Val-Glu-Pro-Ile-COOH, Y-P-F-V-E-P-I, YPFVEPI
Definition: A seven amino acid oligopeptide fragment of the human milk protein, beta-casein. It is an inhibitor of pancreatic elastase, 5-HT2-serotonin receptors, mu-opioid receptors and delta-opioid receptors.
Ontology: Chebi [CHEBI:149635]
Publication: Singh et al., 2020