| ZFIN ID: ZDB-EXP-210125-6 |
Experiment Conditions Description: chemical treatment: DAPT, chemical treatment: N-phenylthiourea
| chemical treatment: DAPT |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | DAPT |
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| Synonyms: | Dapt, gamma-secretase inhibitor IX, tert-butyl (2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)acetate, tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate |
| Definition: | A dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. A gamma-secretase inhibitor. |
| Ontology: | ChEBI [CHEBI:86193] ( EBI ) |
| chemical treatment: N-phenylthiourea |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | N-phenylthiourea |
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| Synonyms: | 1-phenyl-2-thiourea, 1-phenylthiourea, alpha-phenylthiourea, monophenyl thiourea, phenyl-2-thiourea, phenylthiocarbamide, phenylthiourea, PhNHC(=S)NH2, PhNHC(S)NH2, PhNHCSNH2, PTC, PTU |
| Definition: | A member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by a phenyl group. Depending on their genetic makeup, humans find it either very bitter-tasting or tasteless. This unusual property resulted in N-phenylthiourea being used in paternity testing prior to the advent of DNA testing. |
| Ontology: | ChEBI [CHEBI:46261] ( EBI ) |
| Publication: | Hsu et al., 2019 |
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