DAPT

Term ID

CHEBI:86193

Synonyms

gamma-secretase inhibitor IX
GSI-IX
tert-butyl (2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)acetate
tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate

Definition

A dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. It is a γ-secretase inhibitor.

References

pubmed:24520550
pubmed:24751889
pubmed:25063285
pubmed:25997279
pubmed:26607252
pubmed:36764280
pubmed:37285694
reaxys:9588440

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from DAPT

Phenotype where environments contain DAPT

Phenotype modified by environments containing DAPT

Phenotype affecting DAPT

Human Disease Model