ZFIN ID: ZDB-EXP-201006-5
Experiment Conditions Description: chemical treatment: clotrimazole, chemical treatment: lonafarnib
chemical treatment: clotrimazole
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: clotrimazole
Synonyms: 1-((2-Chlorophenyl)diphenylmethyl)-1H-imidazole, 1-(alpha-(2-Chlorophenyl)benzhydryl)imidazole, 1-(o-Chloro-alpha,alpha-diphenylbenzyl)imidazole, 1-(o-Chlorotrityl)imidazole, 1-[(2-chlorophenyl)(diphenyl)methyl]-1H-imidazole, Clotrimazole, Lotrimin (TN), Mycelex (TN)
Definition: A member of the class of imidazoles that is 1H-imidazole in which the hydrogen attached to a nitrogen is replaced by a monochlorotrityl group.
Ontology: ChEBI [CHEBI:3764]  ( EBI )
chemical treatment: lonafarnib
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: lonafarnib
Synonyms: 4-(2-{4-[(11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidin-1-yl}-2-oxoethyl)piperidine-1-carboxamide, lonafarnib, lonafarnibum, SCH 66336
Definition: A 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide that has R configuration. It is used as oral farnesyltransferase inhibitor.
Ontology: ChEBI [CHEBI:47097]  ( EBI )
Publication: Precazzini et al., 2019