lonafarnib

Term ID

CHEBI:47097

Synonyms

• 4-(2-{4-[(11R)-3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidin-1-yl}-2-oxoethyl)piperidine-1-carboxamide
• lonafarnib
• lonafarnibum
• SCH 66336

Definition

A 4-{2-[4-(3,10-dibromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperidin-1-yl]-2-oxoethyl}piperidine-1-carboxamide that has R configuration. It is used as oral farnesyltransferase inhibitor.

References

• cas:193275-84-2
• kegg.drug:D04768
• pdb-ccd:336
• pubmed:10379665
• pubmed:11120601
• pubmed:16732721
• pubmed:17966839
• pubmed:22620979
• pubmed:23897869
• pubmed:25853815
• pubmed:26033044
• pubmed:26189433
• pubmed:26189435
• pubmed:9810004
• reaxys:8244925
• wikipedia.en:Lonafarnib

Ontology

ChEBI  ( EBI )