ZFIN ID: ZDB-EXP-200918-6
Experiment Conditions Description: surgical manipulation: trunk, chemical treatment: cortisol
surgical manipulation: trunk
Name: surgical manipulation
Synonyms:
Definition: Experimental condition that involves manual or instrumental techniques to alter anatomical structures.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000176]
Name: trunk
Synonyms:
Definition: Organism subdivision which is the part of the body posterior to the head and anterior to the post-vent region.
Ontology: Anatomy Ontology [ZFA:0001115]
chemical treatment: cortisol
Name: chemical treatment
Synonyms:
Definition: Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000111]
Name: cortisol
Synonyms: (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17,21-trihydroxypregn-4-ene-3,20-dione, 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione, 11beta-hydrocortisone, 17-hydroxycorticosterone, 4-pregnen-11beta,17alpha,21-triol-3,20-dione, cortisol, hidrocortisona, Hydrocortisone, hydrocortisonum, Kendall's compound F, Reichstein's substance M
Definition: A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses.
Ontology: ChEBI [CHEBI:17650]  ( EBI )
Publication: Gurevich et al., 2019