| ZFIN ID: ZDB-EXP-200917-4 |
Experiment Conditions Description: chemical treatment: DAPT, chemical treatment: semaxanib
| chemical treatment: DAPT |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | DAPT |
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| Synonyms: | Dapt, gamma-secretase inhibitor IX, tert-butyl (2S)-({N-[(3,5-difluorophenyl)acetyl]-L-alanyl}amino)(phenyl)acetate, tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate |
| Definition: | A dipeptide consisting of alanylphenylglycine derivatised as a 3,5-difluorophenylacetamide at the amino terminal and a tert-butyl ester at the carboxy terminal. A gamma-secretase inhibitor. |
| Ontology: | ChEBI [CHEBI:86193] ( EBI ) |
| chemical treatment: semaxanib |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | semaxanib |
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| Synonyms: | (3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-1,3-dihydro-2H-indol-2-one, (Z)-SU 5416, 3-((Z)-(3,5-Dimethylpyrrol-2-yl)methylene)-2-indolinone, 3-(1-(3,5-Dimethyl-1H-pyrrol-2-yl)meth-(Z)-ylidene)-2-oxo-2,3-dihydroindole, 3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-2-indolinone, semaxanib, SU 5416, SU5416, TSU 16 |
| Definition: | An oxindole that is 3-methyleneoxindole in which one of the hydrogens of the methylene group is replaced by a 3,5-dimethylpyrrol-2-yl group. |
| Ontology: | ChEBI [CHEBI:91083] ( EBI ) |
| Publication: | Page et al., 2019 |
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