| ZFIN ID: ZDB-EXP-191206-2 |
Experiment Conditions Description: laceration: pericardial region, chemical treatment by environment: ruxolitinib
| laceration: pericardial region |
|---|
| Name: | laceration |
|---|---|
| Synonyms: | |
| Definition: | Experimental condition in which there is a deep cut or tear of the flesh. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000174] |
| Name: | pericardial region |
|---|---|
| Synonyms: | |
| Definition: | An anatomical cluster composed of the heart and associated structures. |
| Ontology: | Anatomy Ontology [ZFA:0007115] |
| chemical treatment by environment: ruxolitinib |
|---|
| Name: | chemical treatment by environment |
|---|---|
| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | ruxolitinib |
|---|---|
| Synonyms: | (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]propanenitrile, INCB018424, ruxolitinib |
| Definition: | A pyrazole substituted at position 1 by a 2-cyano-1-cyclopentylethyl group and at position 3 by a pyrrolo[2,3-d]pyrimidin-4-yl group. Used as the phosphate salt for the treatment of patients with intermediate or high-risk myelofibrosis, including primary myelofibrosis, post-polycythemia vera myelofibrosis and post-essential thrombocythemia myelofibrosis. |
| Ontology: | ChEBI [CHEBI:66919] ( EBI ) |
| Publication: | Bise et al., 2019 |
|---|