| ZFIN ID: ZDB-EXP-191120-6 |
Experiment Conditions Description: chemical treatment by environment: tiagabine, chemical treatment by environment: pentetrazol
| chemical treatment by environment: tiagabine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | tiagabine |
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| Synonyms: | (-)-(R)-1-(4,4-bis(3-methyl-2-thienyl)-3-butenyl)nipecotic acid, (-)-(R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]nipecotic acid, (3R)-1-[4,4-bis(3-methyl-2-thienyl)but-3-en-1-yl]piperidine-3-carboxylic acid, (R)-(-)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]nipecotic acid, (R)-tiagabine, tiagabina, tiagabine, tiagabinum |
| Definition: | A piperidinemonocarboxylic acid that is (R)-nipecotic acid in which the hydrogen attached to the nitrogen has been replaced by a 1,1-bis(3-methyl-2-thienyl)but-1-en-4-yl group. A GABA reuptake inhibitor, it is used (generally as the hydrochloride salt) for the treatment of epilepsy. |
| Ontology: | ChEBI [CHEBI:9586] ( EBI ) |
| chemical treatment by environment: pentetrazol |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | pentetrazol |
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| Synonyms: | 1,5-pentamethylenetetrazole, 6,7,8,9-tetrahydro-5-azepotetrazole, 6,7,8,9-tetrahydro-5H-tetrazolo[1,5-a]azepine, 7,8,9,10-tetrazabicyclo[5.3.0]-8,10-decadiene, alpha,beta-cyclopentamethylenetetrazole, Cardiazol, Cardiazole, Cardifortan, Cardiotonicum, Cardosal, Cardosan, Cenalene-M, Cenazol, Coranormol, Coratoline, Corazol, Corazole, Corvasol, Coryvet, Deumacard, Diovascole, Gewazol, Kardiazol, Korazol, Metrazol, pentamethylene-1,5-tetrazole, pentetrazol, pentetrazolum, pentylenetetrazol, Pentylenetetrazole, Phrenazol, Ventrazol |
| Definition: | An organic heterobicyclic compound that is 1H-tetrazole in which the hydrogens at positions 1 and 5 are replaced by a pentane-1,5-diyl group. A central and respiratory stimulant, it was formerly used for the treatment of cough and other respiratory tract disorders, cardiovascular disorders including hypotension, and pruritis. |
| Ontology: | ChEBI [CHEBI:34910] ( EBI ) |
| Publication: | Ibhazehiebo et al., 2018 |
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