| ZFIN ID: ZDB-EXP-191001-1 |
Experiment Conditions Description: chemical treatment by environment: 3,3',5-triiodo-L-thyronine, chemical treatment by environment: thyroxine, chemical treatment: N-phenylthiourea
| chemical treatment by environment: 3,3',5-triiodo-L-thyronine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | 3,3',5-triiodo-L-thyronine |
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| Synonyms: | 3,3',5-triiodo-L-thyronine, 3,5,3'-Triiodo-L-thyronine, 3,5,3'-Triiodothyronine, 3,5,3'TRIIODOTHYRONINE, 4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine, L-3,5,3'-Triiodothyronine, L-T3, liothyronine, liothyroninum, liotironina, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, T3, Tertroxin, Tresitope, Triiodothyronine |
| Definition: | An iodothyronine compound having iodo substituents at the 3-, 3'- and 5-positions. Although some is produced in the thyroid, most of the 3,3',5-triiodo-L-thyronine in the body is generated by mono-deiodination of L-thyroxine in the peripheral tissues. Its metabolic activity is about 3 to 5 times that of L-thyroxine. The sodium salt is used in the treatment of hypothyroidism. |
| Ontology: | ChEBI [CHEBI:18258] ( EBI ) |
| chemical treatment by environment: thyroxine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | thyroxine |
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| Synonyms: | 2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid, DL-Thyroxine, O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-DL-tyrosine, Thx, thyroxine |
| Definition: | An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions. |
| Ontology: | ChEBI [CHEBI:30660] ( EBI ) |
| chemical treatment: N-phenylthiourea |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | N-phenylthiourea |
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| Synonyms: | 1-phenyl-2-thiourea, 1-phenylthiourea, alpha-phenylthiourea, monophenyl thiourea, phenyl-2-thiourea, phenylthiocarbamide, phenylthiourea, PhNHC(=S)NH2, PhNHC(S)NH2, PhNHCSNH2, PTC, PTU |
| Definition: | A member of the class of thioureas that is thiourea in which one of the hydrogens is replaced by a phenyl group. Depending on their genetic makeup, humans find it either very bitter-tasting or tasteless. This unusual property resulted in N-phenylthiourea being used in paternity testing prior to the advent of DNA testing. |
| Ontology: | ChEBI [CHEBI:46261] ( EBI ) |
| Publication: | Bohnsack et al., 2013 |
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