ZFIN ID: ZDB-EXP-190924-5
Experiment Conditions Description: chemical treatment by environment: VPC 23019
chemical treatment by environment: VPC 23019
Name: chemical treatment by environment
Synonyms:
Definition: Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water.
Ontology: Zebrafish Environment Condition Ontology [ZECO:0000238]
Name: VPC 23019
Synonyms: (2R)-2-amino-3-(3-octylanilino)-3-oxopropyl dihydrogen phosphate, (2R)-2-amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamide, (R)-phosphoric acid mono-[2-amino-2-(3-octyl-phenylcarbamoyl)-ethyl] ester, N-(3-octylphenyl)-O-phosphono-D-serinamide, VPC-23019, VPC23019
Definition: A secondary carboxamide resulting from the formal condensation of the carboxy group of O-phospho-D-serine with the amino group of m-octylaniline. An analogue of sphingosine-1-phosphate (S1P), it is a potent antagonist for both S1P1 and S1P3 receptors. It can inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells.
Ontology: ChEBI [CHEBI:144948]  ( EBI )
Publication: Hübner et al., 2018