Search Ontology:
ChEBI
VPC 23019
- Term ID
- CHEBI:144948
- Synonyms
-
- (2R)-2-amino-3-(3-octylanilino)-3-oxopropyl dihydrogen phosphate
- (2R)-2-amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamide
- (R)-phosphoric acid mono-[2-amino-2-(3-octyl-phenylcarbamoyl)-ethyl] ester
- N-(3-octylphenyl)-O-phosphono-D-serinamide
- VPC-23019
- VPC23019
- Definition
- A secondary carboxamide resulting from the formal condensation of the carboxy group of O-phospho-D-serine with the amino group of m-octylaniline. An analogue of sphingosine-1-phosphate (S1P), it is a potent antagonist for both S1P1 and S1P3 receptors. It can inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells.
- References
-
- cas:449173-19-7
- pubmed:15590668
- pubmed:20097776
- pubmed:23360427
- pubmed:24586752
- pubmed:24814049
- pubmed:25880547
- pubmed:26079370
- pubmed:26943364
- pubmed:27605019
- pubmed:29150495
- pubmed:29790626
- pubmed:30192865
- pubmed:30629456
- pubmed:30680029
- pubmed:30782093
- pubmed:30877755
- pubmed:31097221
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from VPC 23019
Phenotype where environments contain VPC 23019
Phenotype modified by environments containing VPC 23019
Phenotype affecting VPC 23019
Human Disease Model