VPC 23019

Term ID

CHEBI:144948

Synonyms

(2R)-2-amino-3-(3-octylanilino)-3-oxopropyl dihydrogen phosphate
(2R)-2-amino-N-(3-octylphenyl)-3-(phosphonooxy)-propanamide
(R)-phosphoric acid mono-[2-amino-2-(3-octyl-phenylcarbamoyl)-ethyl] ester
N-(3-octylphenyl)-O-phosphono-D-serinamide
VPC-23019
VPC23019

Definition

A secondary carboxamide resulting from the formal condensation of the carboxy group of O-phospho-D-serine with the amino group of m-octylaniline. An analogue of sphingosine-1-phosphate (S1P), it is a potent antagonist for both S1P1 and S1P3 receptors. It can inhibit S1P-induced migration of thyroid cancer cells, ovarian cancer cells, and neural stem cells.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: aromatic amide D-serine derivative organic phosphate phosphoric ester secondary carboxamide

aromatic amide D-serine derivative organic phosphate phosphoric ester secondary carboxamide Show first 5 Terms
has_functional_parent: O-phospho-D-serine

O-phospho-D-serine Show first 5 Terms
has_role: sphingosine-1-phosphate receptor 1 antagonist sphingosine-1-phosphate receptor 3 antagonist

sphingosine-1-phosphate receptor 1 antagonist sphingosine-1-phosphate receptor 3 antagonist Show first 5 Terms

Phenotype

Phenotype resulting from VPC 23019

Phenotype where environments contain VPC 23019

Phenotype modified by environments containing VPC 23019

Human Disease Model