| ZFIN ID: ZDB-EXP-190627-22 |
Experiment Conditions Description: chemical treatment by environment: L-dopa, chemical treatment by environment: alpha-methyl-L-tyrosine
| chemical treatment by environment: L-dopa |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | L-dopa |
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| Synonyms: | (-)-3-(3,4-dihydroxyphenyl)-L-alanine, (-)-dopa, (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid, 3,4-Dihydroxy-L-phenylalanine, 3,4-DIHYDROXYPHENYLALANINE, 3-Hydroxy-L-tyrosine, beta-(3,4-dihydroxyphenyl)-L-alanine, beta-(3,4-dihydroxyphenyl)alanine, Dihydroxy-L-phenylalanine, Dopar, L-beta-(3,4-Dihydroxyphenyl)alanine, L-DOPA, levodopa, levodopum |
| Definition: | An optically active form of dopa having L-configuration. Used to treat the stiffness, tremors, spasms, and poor muscle control of Parkinson's disease |
| Ontology: | ChEBI [CHEBI:15765] ( EBI ) |
| chemical treatment by environment: alpha-methyl-L-tyrosine |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | alpha-methyl-L-tyrosine |
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| Synonyms: | (-)-alpha-Methyl-L-tyrosine, (S)-alpha-Methyltyrosine, alpha-methyl-L-p-tyrosine, alpha-methyl-L-tyrosine, alpha-methyl-p-tyrosine, alpha-methyl-para-tyrosine, alpha-Methyltyrosine, L-alpha-Methyltyrosine, Methyltyrosine, metirosina, metirosine, metirosinum, Metyrosine |
| Definition: | An L-tyrosine derivative that consists of L-tyrosine bearing an additional methyl substituent at position 2. An inhibitor of the enzyme tyrosine 3-monooxygenase, and consequently of the synthesis of catecholamines. It is used to control the symptoms of excessive sympathetic stimulation in patients with pheochromocytoma. |
| Ontology: | ChEBI [CHEBI:6912] ( EBI ) |
| Publication: | Tanaka et al., 2018 |
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