| ZFIN ID: ZDB-EXP-180725-2 |
Experiment Conditions Description: chemical treatment: phosphonoformic acid
| chemical treatment: phosphonoformic acid |
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| Name: | chemical treatment |
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| Synonyms: | |
| Definition: | Experimental condition in which the fish is treated with a chemical substance. This treatment could be administered by adding the chemical substance to the tank water, injections, or by consumption. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000111] |
| Name: | phosphonoformic acid |
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| Synonyms: | carboxyphosphonic acid, dihydroxyphosphanecarboxylic acid oxide, Foscarmet, Foscarnet, PHOSPHONOFORMIC ACID, phosphonomethanoic acid |
| Definition: | Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity. |
| Ontology: | ChEBI [CHEBI:127780] ( EBI ) |
| Publication: | Chernyavskaya et al., 2017 |
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