Search Ontology:
ChEBI

phosphonoformic acid

Term ID
CHEBI:127780
Synonyms
  • carboxyphosphonic acid
  • dihydroxyphosphanecarboxylic acid oxide
  • Foscarmet
  • Foscarnet
  • PHOSPHONOFORMIC ACID
  • phosphonomethanoic acid
Definition
Phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_functional_parent
has_role
inverse has_functional_parent
inverse is_conjugate_base_of
is_conjugate_acid_of
Phenotype
Phenotype resulting from phosphonoformic acid
Phenotype where environments contain phosphonoformic acid
Phenotype modified by environments containing phosphonoformic acid
Human Disease / Model Data
Citations
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