| ZFIN ID: ZDB-EXP-180306-3 |
Experiment Conditions Description: chemical treatment by environment: everolimus
| chemical treatment by environment: everolimus |
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| Name: | chemical treatment by environment |
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| Synonyms: | |
| Definition: | Chemical treatment condition in which the chemical is introduced through the environment. For zebrafish this is the tank water. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000238] |
| Name: | everolimus |
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| Synonyms: | (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,35R)-1,18-dihydroxy-12-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.0(4,9)]hexatriaconta-16,24,26,, (3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]propan-2-yl}-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-3, 40-O-(2-hydroxyethyl)-rapamycin, 42-O-(2-hydroxyethyl)rapamycin, Afinitor, Afinitor Disperz, Certican, Everolimus, everolimusum, RAD 001, RAD001, SDZ RAD, SDZ-RAD, Votubia, Xience V, Zortress |
| Definition: | A macrocyclic lactone that is rapamycin in which the hydroxy group attached to the cyclohexyl moiety has been converted into the corresponding 2-hydroxyethyl ether. It is an immunosuppressant and antineoplastic agent. |
| Ontology: | ChEBI [CHEBI:68478] ( EBI ) |
| Publication: | Mans et al., 2017 |
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