| ZFIN ID: ZDB-EXP-171110-5 |
Experiment Conditions Description: chemical treatment by gavage: vemurafenib, gamma ray, cancer xenotransplantation
| chemical treatment by gavage: vemurafenib |
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| Name: | chemical treatment by gavage |
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| Synonyms: | |
| Definition: | Chemical treatment condition where the chemical is introduced to the organism by gavage. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000255] |
| Name: | vemurafenib |
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| Synonyms: | N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide, PLX 4032, PLX-4032, PLX4032, RG 7204, RG-7204, RG7204, Ro 51-85426, RO 5185426, RO-51-85426, RO-5185426, RO5185426, vemurafenib, vemurafenibum, Zelboraf |
| Definition: | A pyrrolopyridine that is 1H-pyrrolo[2,3-b]pyridine which is substituted at position 5 by a p-chlorophenyl group and at positions 3 by a 3-amino-2,6-difluorobenzoyl group, the amino group of which has undergone formal condensation with propane-1-sulfonic acid to give the corresponding sulfonamide. An inhibitor of BRAF and other kinases. |
| Ontology: | ChEBI [CHEBI:63637] ( EBI ) |
| gamma ray |
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| Name: | gamma ray |
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| Synonyms: | |
| Definition: | |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000216] |
| cancer xenotransplantation |
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| Name: | cancer xenotransplantation |
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| Synonyms: | |
| Definition: | Xenotransplantation condition in which cancer cells are injected or grafted into the zebrafish. |
| Ontology: | Zebrafish Environment Condition Ontology [ZECO:0000236] |
| Publication: | Dang et al., 2016 |
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