Search Ontology:
ChEBI

vemurafenib

Term ID
CHEBI:63637
Synonyms
  • N-(3-{[5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl}-2,4-difluorophenyl)propane-1-sulfonamide
  • PLX 4032
  • PLX-4032
  • PLX4032
  • RG 7204
  • RG-7204
  • RG7204
  • Ro 51-85426
  • RO 5185426
  • RO-51-85426
  • RO-5185426
  • RO5185426
  • vemurafenib
  • vemurafenibum
  • Zelboraf
Definition
A pyrrolopyridine that is 1H-pyrrolo[2,3-b]pyridine which is substituted at position 5 by a p-chlorophenyl group and at positions 3 by a 3-amino-2,6-difluorobenzoyl group, the amino group of which has undergone formal condensation with propane-1-sulfonic acid to give the corresponding sulfonamide. An inhibitor of BRAF and other kinases.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from vemurafenib
Phenotype where environments contain vemurafenib
Phenotype modified by environments containing vemurafenib
Human Disease / Model Data
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